Honey Garlic Salmon and Brussels Sprouts (35-Minutes)

Looking for a quick, healthy, and incredibly delicious sheet pan meal?
This honey garlic salmon and Brussel sprouts recipe is the perfect choice for busy weeknights.
With crispy, caramelized Brussels sprouts and tender, flaky salmon coated in a rich, garlicky honey glaze, this dish is packed with flavor and nutrition.
Plus, it comes together in just 35 minutes with minimal cleanup.
Whether you love one-pan dinners, enjoy easy salmon recipes, or want a nutritious meal with protein and veggies, this recipe delivers on all fronts.
Why You’ll Love This Recipe
- One-pan convenience – Easy preparation and minimal dishes to clean
- Packed with flavor – A perfect balance of sweet, savory, and garlicky goodness
- Healthy & nutritious – High-protein salmon and fiber-rich Brussels sprouts
- Quick & easy – Ready in just 35 minutes
Ingredients
For the Salmon & Brussels Sprouts:
- 4 salmon fillets (skin-on or skinless)
- 1 pound Brussels sprouts, trimmed and halved
- 2 tablespoons olive oil
- Salt and black pepper, to taste
For the Honey Garlic Glaze:
- 3 tablespoons honey
- 3 cloves garlic, minced
- 2 tablespoons soy sauce
- 1 tablespoon Dijon mustard
- 1 tablespoon lemon juice
- ½ teaspoon red pepper flakes (optional)
How to Make Honey Garlic Salmon and Brussels Sprouts
Step 1: Prep the Ingredients
- Preheat the oven to 400°F (200°C).
- Line a baking sheet with parchment paper or aluminum foil for easy cleanup.
- Trim and halve the Brussels sprouts.
Step 2: Make the Honey Garlic Glaze
- In a small bowl, whisk together honey, garlic, soy sauce, Dijon mustard, lemon juice, and red pepper flakes.
- Set aside for basting later.
Step 3: Roast the Brussels Sprouts
- Place the Brussels sprouts on the prepared baking sheet.
- Drizzle with olive oil, season with salt and black pepper, and toss to coat.
- Spread them out in an even layer and roast for 15 minutes.
Step 4: Add the Salmon and Glaze Everything
- Remove the sheet pan from the oven and push the Brussels sprouts to one side.
- Place the salmon fillets on the other side.
- Brush the salmon generously with the honey garlic glaze.
- Return to the oven and bake for another 10-12 minutes, or until the salmon is cooked through and flakes easily with a fork.
Step 5: Broil for Extra Caramelization (Optional)
- For crispy edges, switch the oven to broil and cook for an additional 1-2 minutes.
- Drizzle with any remaining glaze before serving.

Tips for the Best Sheet Pan Salmon and Brussels Sprouts
- Use fresh salmon for the best texture and flavor.
- Don’t overcrowd the pan to ensure even roasting.
- Broil at the end for a caramelized finish.
- Add other veggies like carrots, green beans, or asparagus for variety.
What to Serve with Honey Garlic Salmon
- Rice or quinoa – To soak up the delicious glaze.
- Mashed potatoes – A creamy and comforting side.
- Cauliflower rice – A low-carb alternative.
- Crispy roasted potatoes – For an extra hearty meal.
Storing & Reheating Leftovers
- Fridge: Store in an airtight container for up to 3 days.
- Freezer: Freeze salmon separately for up to 2 months.
- Reheat: Warm in a 350°F oven for 10 minutes or microwave in short bursts until heated through.
Recipe FAQ’s
Can I use frozen salmon?
Yes, just thaw it completely before cooking for the best results.
Can I substitute the Brussels sprouts?
Absolutely. Try broccoli, asparagus, or green beans as alternatives.
How do I know when salmon is done?
The salmon should be flaky and opaque with an internal temperature of 145°F (63°C).

Honey Garlic Salmon and Brussels Sprouts
This honey garlic salmon and Brussels sprouts recipe proves that healthy eating can be both simple and delicious. With a sweet-savory glaze, crispy Brussels sprouts, and tender salmon, it’s a perfect one-pan meal for any night of the week.
For the Salmon & Brussels Sprouts:
- 4 salmon fillets skin-on or skinless
- 1 pound Brussels sprouts trimmed and halved
- 2 tablespoons olive oil
- Salt and black pepper to taste
For the Honey Garlic Glaze:
- 3 tablespoons honey
- 3 cloves garlic minced
- 2 tablespoons soy sauce
- 1 tablespoon Dijon mustard
- 1 tablespoon lemon juice
- ½ teaspoon red pepper flakes optional
Step 1: Prep the Ingredients
- Preheat the oven to 400°F (200°C).
- Line a baking sheet with parchment paper or aluminum foil for easy cleanup.
- Trim and halve the Brussels sprouts.
Step 2: Make the Honey Garlic Glaze
- In a small bowl, whisk together honey, garlic, soy sauce, Dijon mustard, lemon juice, and red pepper flakes.
- Set aside for basting later.
Step 3: Roast the Brussels Sprouts
- Place the Brussels sprouts on the prepared baking sheet.
- Drizzle with olive oil, season with salt and black pepper, and toss to coat.
- Spread them out in an even layer and roast for 15 minutes.
Step 4: Add the Salmon and Glaze Everything
- Remove the sheet pan from the oven and push the Brussels sprouts to one side.
- Place the salmon fillets on the other side.
- Brush the salmon generously with the honey garlic glaze.
- Return to the oven and bake for another 10-12 minutes, or until the salmon is cooked through and flakes easily with a fork.
Step 5: Broil for Extra Caramelization (Optional)
- For crispy edges, switch the oven to broil and cook for an additional 1-2 minutes.
- Drizzle with any remaining glaze before serving.